Pep Guardiola's men host Burnley on Saturday 18 March, with kick-off scheduled for 17:45 (UK).
The visitors - runaway leaders at the top of the Championship - are managed by former City captain Vincent Kompany, who spent 11 trophy-laden years at the Club between 2008 and 2019.
He was part of the team who claimed the FA Cup in 2011 - our first major trophy in 35 years - before leading us to an historic Premier League triumph as captain the following year.
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Kompany went on to win a further ten domestic honours at City before moving back to his native Belgium to become player-coach at his first club, Anderlecht.
He's sure to receive a hero's welcome when he returns to the Etihad on Saturday but, once the match gets under way, all pleasantries will be put to one side.
With the reward for victory being a place in the semi-finals, there is plenty at stake between two of English football's in-form sides.
City enter the tie on the back of five straight wins in all competitions as we aim to reach Wembley for a fifth-successive season, while Burnley are yet to taste defeat in 2023.
Everything points towards a thrilling encounter at the Etihad. Get in the matchday mood via the video above...